best bone marrow transplant in india

A bone marrow transplant is a procedure that replaces damaged or diseased bone marrow with healthy marrow. A bone marrow transplant is also known as a stem cell transplant. Damaged bone marrow produces insufficient blood cells, which leads to certain disorders and cancer. Therefore, the need to get a transplant arises. However, it also entails a lengthy recovery period and the possibility of major adverse effects.

What is the purpose of a Bone Marrow Transplant?

The transplanted marrow begins as hematopoietic stem cells. They are relatively immature but can develop into a variety of blood cells. They enter your blood once they have matured after leaving the bone marrow. Hematopoietic stem cells can develop into:

  • Red blood cells: The work of the Red blood cells is to transport oxygen throughout your body.
  • White blood cells: They are the cells that aid in the immune system’s function.
  • Platelets: The work of Platelets is to allow your blood to clot to prevent bleeding.

What can a Bone Marrow Transplant help with?

A bone marrow transplant can help with:

  • Replacing stem cells that have been killed by cancer treatment.
  • Replacing damaged marrow that is incapable of producing its own stem cells.
  • Detecting and eliminating cancer cells. 

When do you need a Bone Marrow Transplant? 

If you have any of these conditions, you may need a bone marrow transplant:

  • Leukemia, whether acute or chronic
  • Lymphoma, whether Hodgkin’s or non- Hodgkin’s
  • Waldenstrom macroglobulinemia
  • Multiple myeloma 
  • Aplastic anemia 
  • Amyloidosis
  • Myelofibrosis
  • Myeloproliferative diseases (MPDs) 
  • Tumors of germ cells
  • Sarcoma

What are the kinds of Bone Marrow Transplants?

Bone marrow transplants can be divided into the following two categories:

  • Autologous: 

While receiving cancer therapy, your medical team takes stem cells from your own marrow or blood and preserves them. The stem cells are then injected into your bloodstream. The cells migrate to your bone marrow and multiply, assisting it in regenerating healthy stem cells.

  • Allogeneic :  

You receive stem cells from a person whose bone marrow closely matches yours. It could be a close relative, such as a parent or sibling, or someone from a national donor registry. A syngeneic transplant occurs when the donor has the same tissue type as you and is  an identical sibling. Doctors can also extract stem cells from a newborn’s umbilical cord blood.

What is the procedure for a Bone Marrow Transplant? 

You will begin with a procedure known as conditioning. This usually entails a strong dose of chemotherapy for around 10 days, sometimes with radiation. It varies from person to person and is determined by your overall health as well as the ailment being treated.

Conditioning frees up space in your bone marrow for new cells to proliferate. It also temporarily weakens your immune system so that your body doesn’t have to fight the new cells.

Conditioning may have the following side effects:

  • Sores in the mouth
  • Vomiting and nausea
  • Having difficulty eating
  • Hair loss 
  • Breathing or lung difficulties
  • Premature menopause 
  • Fertility issues

You will receive new blood stem cells through the central venous catheter after a few days of rest. You’ll most likely be awake through this, but it shouldn’t be too painful.

The new cells will mature into red and white blood cells, as well as platelets, once they reach your marrow. This procedure, known as engraftment, can take anywhere from two to four weeks.

Recovery after a Bone Marrow Transplant

Everyone’s recovery is different, but you’ll most likely be in the hospital for several weeks. Your immune system will become weak, so you will be prescribed antibiotics to avoid infection. Blood transfusions may also be required.

The doctors who conduct the best bone marrow transplant in India will test your blood frequently for engraftment throughout the first few weeks. For this, they may take a little sample of your bone marrow. You can leave the hospital after meeting certain conditions, such as specified blood cell counts and no fever for two days. You’ll also need someone at home to assist you with your care. After your transplant, your immune system may take a year or longer to heal. To avoid infections and graft-vs.-host disease, you’ll need to see your doctor frequently and continue taking your medicines. 

You may be referred to a dietician by your medical team. They can help you develop a food plan that will help you avoid illnesses and stay healthy. They might advise you to:

  • Avoid foods and beverages with a higher risk of foodborne illness.
  • Select foods that provide your body with the nutrition it requires.
  • To fill nutritional gaps, take multivitamins or supplements.
  • Limit your sodium intake.
  • Avoid consuming alcoholic beverages.
  • Observe general food safety precautions.

For a while, you won’t be able to return to work or other activities. Your doctor can also advise you to make some adjustments in your lifestyle. 

What are the risks involved in a Bone Marrow Transplant? 

Complications from a Bone Marrow Transplant include:

  • Bleeding\Infection
  • Low cell numbers in the blood
  • Diarrhea 
  • Fertility issues
  • Cataracts
  • Leg cramps or muscle spasms
  • A feeling of numbness in your arms or legs
  • Inflammation of the mouth and digestive tract
  • Problems with the liver or kidneys
  • Breathing problems
  • Damage to the organs

What are the outlooks for a Bone Marrow Transplant? 

A bone marrow transplant’s success is determined by a number of factors, like : 

  • Your age
  • Your general well-being
  • The procedure you had
  • The effect of the procedure on your illness
  • Your tolerance to the procedure
  • If you are facing any new issues

In conclusion, thousands of patients have been healed of their illnesses thanks to bone marrow transplants. Doctors who conduct the best bone marrow transplant in India are also developing novel techniques to help them. This only increases the chances of success making bone marrow transplant a reliable procedure to follow if the need arises.

By Adam

Leave a Reply

Your email address will not be published.